How does Fertomid (Clomifene) work:

Fertomid (Clomifene) inhibits the negative feedback mechanisms of oestrogens in the hypothalamus and pituitary which stimulates the secretion of pituitary gonadotrophic hormones resulting in stimulation of ovulation.

Fertomid (Clomifene) is an estrogen receptor-blocker that increases the secretion of a certain hormone, known as gonadotropin-releasing hormone, which blocks estrogen. Typically, clomifene is used to induce ovulation in women who do not produce eggs but desire to become pregnant.

In a study by a Japanese researcher, fifty-nine men with abnormal sperm where tested. Thirty-six men received a gonadotropin-releasing hormone analogue and twenty-three men patients received oral clomiphene for three months. Sperm density increased in men treated with the hormone analogue, but no significant change in sperm density occurred in men treated with clomifene.

Dosage & Administration:

ADULT: 50 mg daily for 5 days starting on the fifth day of the menstrual cycle or at any time if there is amenorrhoea. If ovulation does not occur, a second course of 100 mg for 5 days may be used commencing as early as 30 days after the previous therapy. Further treatment may not be advised, if pregnancy has not occurred after a total of 6 treatment cycles.

Side Effects:

• Hypersensitivity
• Abnormal bleeding
• Pregnancy, lactation
• Liver dysfunction
• Uncontrolled thyroid or adrenal dysfunction, patients with an organic intracranial lesions such as pituitary tumor