How does Melanorm (Hydroquinone) work:

Melanorm (Hydroquinone) is a skin-bleaching agent that is used to lighten areas of darkened skin such as freckles, chloasma (also known as melasma), age spots, and acne scars. Melanorm (Hydroquinone) works by decreasing the production and increasing the breakdown of melanosomes (melanin pigment granules) in the skin's pigment cells (melanocytes). It does this by inhibiting the activity of tyrosinase, the enzyme needed to make melanin.

Dosage & Administration:

Test for skin sensitivity before using by applying the cream to a small patch of hyperpigmented skin. If no redness or itching occurs within 24 hours, begin treatment. Clean and dry the skin before applying a thin film of cream twice daily to the area(s) in need of bleaching. Rub into the skin well. Apply just enough to cover the affected areas and avoid applying to normal skin, as this will lighten as well. Hence wash your hands after applying unless these are areas of treatment. When using non-medicated cosmetics, sunscreens, and moisturising lotions, apply Melanorm (Hydroquinone) first, then wait several minutes before applying them over the top.

Side Effects:

• mild itching
• stinging and reddening of the skin
• burning
• crusting
• swelling
• unusual skin discolouration
• development of exogenous ochronosis (a persistent blue-black pigmentation)
• ochronosis

Precautions:

Do not use benzoyl peroxide, hydrogen peroxide, or other peroxide products when using Melanorm (Hydroquinone). A temporary dark staining of the skin may occur. If accidentally used together, wash the skin with soap and water to remove the staining. Melanorm (Hydroquinone) may contain sodium metabisulphite that may cause serious allergic reactions (including anaphylaxis) in certain susceptible people. Melanorm (Hydroquinone) should not be used in pregnancy or when breastfeeding.

Further Information of Melanorm-HC (Hydroquinone Acetate/Tretinoin):

Melanorm-HC is a combination cream containing:

• Hydroquinone (2%)
• Tretinoin (0.025%)
• Hydrocortisone (1%)