Active Ingredient	Albendazole IP
Manufacturer	GlaxoSmithKline
Origin	New Zealand
Other Names	N/A
Reference	N/A

How does Zentel (Albendazole IP) work:

Zentel (Albendazole) is an oral drug designed to treat different kinds of worm infections. The active ingredient Albendazole is an anthelmintic and works by killing sensitive parasites. It is designed to successfully clear threadworms, pinworms, roundworms, whipworms, tapeworms and hookworms from the gut and other tissues. Zentel is thought to kill these worms by causing them to starve. The eggs, larvae and adult worms are affected.

The main generic of Zentel, Albendazole, works to injure the worms and fight the infection. Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. The parasite is immobilized and eventuelly dies.

Dosage & Administration:

For your individual dosage discuss yourself with your physician. He can advise you on how many tablets you should take each day and for how long it is suitable to take Zentel. The common dosage for adults and children older than 2 years, are two tablets (single dose). It is important to always take the full course of tablets, and not to immediately stop the medication when ones feel better. This way one can make sure that Zentel works. Sometimes a second dose or course of Zentel is necessary.

Take your dosage with food or on an empty stomach. It is important to take the tablets on an empty stomach. Although in some conditions and as particularly advised by your physician the tablets may need to be taken after food. Zentel tablets can be taken crushed or chewed or swallowed in one whole. It is no special laxative or fasting is needed.

In case you forget to take your dosage, take the missed tablets as soon as you remember to take them. If your physician had prescribed to you more than a single dose, don not try to make the missed dosasge by applying more than two tablets at a time. Follow your physicians' instructions about how and when to use Zentel. If you have any concerns about how to take this medicine, talk to your physician or pharmacist. He may need to see you two to four weeks after taking the dose or course.

Side Effects:

As specified below there are certain side effects aligned with Zentel. In case you do observe any unwished effects, do consult your physician or pharmacist, because some of these side effects may need medical assistance.

• Nausea
• Vomitting
• Dizziness
• Headaque
• Insomnia
• Infection
• Stomach pain
• Aggression
• Temporary hair loss

Precautions:

There are some medical conditions which might interact with Zentel. Speak to your physician in case you are pregnant, if you are planning a pregnancy or if you are breast feeding. Further it is advised to speak first to a medical supervisor if:

• Allergies to medicines
• Allergies to foods or other substances
• Liver problems
• Eye bone marrow problem
• Low white blood cell
• Low platelet
• One is taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

Immediately tell your physician if you observe the mentioned bellow:

• Fever
• Bonepain
• Headache
• Tiredness
• Shortness of Breath
• Looking pale
• Unusual bleeding or bruising
• Infections of the throat
• Infections of the mouth, skin or nasal passage

Further Information:

Always keep the tablets in the original pack until it is time to take them. Store the package in a cool dry place. Never store this medicine in the bathroom or near a sink (Heat and dampness can destroy some medicines) Keep the medicines out of the reach of children.