How does 9 PM Eye Drops (Latanoprost) work:

9 PM Eye Drops (Latanoprost) is a prostaglandin F2 (alpha) analogue. Latanoprost is a prostanoid selective FP receptor agonist which is believed to reduce the intraocular pressure by increasing the outflow of aqueous humor. Studies in animals and man suggest that the main mechanism of action is increased uveoscleral outflow. 9 PM Eye Drops is indicated for the reduction of elevated intraocular pressure in patients with open angle glaucoma and ocular hypertension.

Dosage & Administration:

The recommended dosage is 1 drop in the affected eye(s) once daily in the evening. The dosage of 9 PM Eye Drops (Latanoprost) should NOT exceed once daily since it has been shown that more frequent administration may decrease the intraocular pressure lowering effect. Reduction of the intraocular pressure starts approximately 3 to 4 hours after administration and the maximum effect is reached after 8 to 12 hours. 9 PM Eye Drops may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Side Effects:

• eyelash changes
• increased length, thickness, pigmentation of eyelashes
• eyelid skin darkening
• intraocular inflammation
• iris pigmentation changes
• macular edema

Precautions:

9 PM Eye Drops (Latanoprost) has been reported to cause changes to pigmented tissues. The most frequently reported changes have been increased pigmentation of the iris and periorbital tissue (eyelid) and increased pigmentation and growth of eyelashes. These changes may be permanent. Latanoprost may gradually change eyelashes (see "Side Effects"). Patients who are expected to receive treatment in only one eye should be informed about the potential for increased brown pigmentation of the iris, periorbital tissue, and eyelashes in the treated eye and thus, heterochromia between the eyes.

Patients should be informed about the possibility of iris color change due to an increase of the brown pigment and resultant cosmetically different eye coloration that may occur when only one eye is treated. Iris pigmentation changes may be more noticeable in patients with green-brown, blue/gray-brown or yellow-brown irises.