How does Daonil (Glibenclamide) work:

Daonil (Glibenclamide) belongs to a group of medicines called sulphonylureas. Daonil is used to control blood glucose levels in patients with type 2 diabetes mellitus. This type of diabetes is also known as non-insulin-dependent diabetes (NIDDM) or maturity onset diabetes. Daonil is used in conjunction with diet control and exercise to control blood sugar. It works by increasing the amount of insulin released by your pancreas.

If your blood glucose is not properly controlled, you may experience hypoglycaemia (low blood glucose) or hyperglycaemia (high blood glucose). High blood glucose can lead to serious problems with your heart, eyes, circulation or kidneys.

Dosage & Administration:

Your physician will tell you how many tablets to take each day. Your physician may change the dose depending on your blood glucose levels.

Take your tablet immediately before breakfast. If you only eat a very light breakfast then this dose should be put off until lunchtime. Swallow the tablets with a glass of water.

Side Effects:

Tell your physician if you notice any of the following and they worry you:

• weakness
• trembling or shaking
• sweating, light headedness
• headache
• dizziness
• lack of concentration
• tearfulness
• numbness around the lips and fingers
• nausea
• vomiting
• heartburn
• indigestion
• cramps
• diarrhoea
• constipation
• a feeling of fullness in the stomach
• loss of appetite
• blurred or double vision
• unusual weight gain

Tell your physician immediately or go to hospital if you notice any of the following:

• convulsions or fits
• deafness
• blindness
• severe pain
• tenderness in the stomach
• sudden onset of abnormal thoughts or delusions
• swelling of the face, lips or tongue
• difficulty in swallowing or breathing
• unexplained weight loss
• trouble breathing
• feeling weak or tired
• uncomfortable, unusual muscle pain
• slow heart beat
• rash, sores, redness or itching of the skin
• itchy hives-like rash or spots
• redness, itching, swelling or blistering
• bleeding or bruising more easily than normal
• reddish or purplish blotches under the skin
• yellowing of the skin or eyes
• fever, severe chills, sore throat or mouth ulcers
• tiredness
• being short of breath
• looking pale
• a change in the colour or amount of urine passed
• blood in the urine

Precautions:

Tell your physician if you have any allergies to any other medicines or any other substances such as foods, preservatives or dyes, or you are breastfeeding or plan to breastfeed. Always talk to your physician if you have or have had kidney problems, liver problems, a history of diabetic coma, adrenal, pituitary (or thyroid) problems or heart failure. Tell your physician if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop.