How does Combivent Inhaler (Ipratropium Bromide / Salbutamol Sulphate) work:

Combivent contains two active ingredients: ipratropium bromide and salbutamol sulphate.

Ipratropium bromide is a type of medicine known as an antimuscarinic bronchodilator. It works by blocking different types of receptors, called muscarinic receptors, which are found on the muscles surrounding the airways in the lungs. As ipratropium blocks the receptors, it stops the action of acetylcholine and allows the airways to open, making it easier to breathe.

Salbutamol sulphate is a short-acting beta 2 agonist. It works by acting on receptors in the lungs called beta 2 receptors. Stimulation of these receptors causes the muscles in the airways to relax, allowing the airways to open.

This combination of medicines has an additive effect in opening the airways, and makes it easier to breathe in conditions where the airways tighten.

Side Effects:

• Headache
• Difficulty in passing urine
• Dry mouth
• Shaking, usually of the hands
• Muscle cramps
• Sweating
• Unexpected narrowing of the airways
• Low blood potassium level
• Awareness of your heartbeat
• Dizziness
• Nausea and vomiting
• Cough
• Nervousness
• Increased heart rate
• Hypersensitivity reactions such as swelling of the lips, throat and tongue (angioedema), itchy blistering rash or anaphylactic shock
  

Further Information:

Please note: For more information about any other possible risks, please consult your physician or pharmacist and read the information provided with Combivent.